Glucosamine Sulfate has been studied in multiple clinical trials and has been shown to significantly improve pain and joint function in patients with arthritis. Glucosamine appears to stimulate the function of normal cells and tissues in the affected joints. Patients on blood thinners should consult a qualified health professional.

Methylsulfonylmethane (MSM) has also been shown to work synergistically with glucosamine sulfate to reduce both the pain and swelling associated with arthritic joints.

Mythocondro® is a nutritional supplement that supports strong and healthy joints. Mythocondro® is the first Non-Animal Chondroitin Sulfate produced by a patented fermentation-based manufacturing process. It has homogeneous structure and a constant charge density and molecular mass parameters, like in human synovial fluid. Mythocondro® has clinically proven superior bioavailability thanks to an improved intestinal epithelial permeability of 43%. It is an effective and safe nutritional supplement that supports strong and healthy joints.

CMO (Cetyl Myristoleate) was shown to decrease pain and increase movement in a clinical study of patients with osteoarthritic joints. It is believed that these fatty acids may lubricate the joints and soften the surrounding tissues. They may also modulate the immune system and function as anti-inflammatory agents.

Hyaluronic Acid by injection has been approved by the FDA for the treatment of osteoporosis. There is evidence of its usefulness in oral form as well. Hyaluronic acid acts as a physical cushion for joints and has antioxidant activity as well. It also acts to improve hydration and wound healing in joints.

Black Catechu also known as Acacia catechu, has been traditionally used as an anti-inflammatory for joint pain. Clinical studies have shown that Black catechu has promise in the treatment of arthritis. It has been shown to inhibit enzymes known to be involved in inflammation and decrease pain in arthritis patients. Black Catechu has also been shown to potentially reduce atherosclerosis (hardening of the arteries). Catechu has 'Generally Recognized As Safe' (GRAS) status for use in food in the US.

L-Glutamic Acid is one of the most abundant amino acids in the body and functions in many different areas, including increasing energy metabolism, skeletal muscle strengthening as well as boosting the immune system. Glutamic acid is also used to synthesize other amino acids and has been found to be useful in tissue repair after surgery or other injury.

L-Cysteine is another amino acid that serves to help rebuild joint structures, including tissue repair and skeletal muscle strength. It has been shown to be safe in a number of clinical studies.

 

White Willow Bark Extract (Salix Alba) contains salicin, which is metabolized to salicylic acid, the active ingredient is aspirin. Salix acts as an anti-inflammatory and pain reliever by inhibiting COX-2 mediated prostaglandin release by indirectly affecting the COX-1 and COX-2 activity. Salix inhibits platelet aggregation, but not to the degree that aspirin and other NSAIDS. It is therefore considered to be an effective pain reliever without the adverse effects of aspirin.

Boswellia Serrata Gum extract has been extensively used as an anti-inflammatory agent and has been researched as a treatment for arthritic conditions in a number of clinical studies.

 

Holy Basil (Ocimum sanctum) acts as an anti-inflammatory agent and is an adaptogen, aiding the body during stress. It also has pain-relieving properties. It has been used in clinical studies for its control of sugar levels in diabetics.

 

Turmeric (Curcuma Langa L Rhizome) also known as curcumin, has been used successfully for thousands of years by practitioners of the Ayurvedic medicine. Turmeric was used as a treatment for stomach ailments, abdominal discomfort, and pain relief — as it turns out, turmeric is an effective anti-inflammatory agent as well. It inhibits the same enzymes that NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) target, but without the side effects. Clinical studies in patients with arthritis have produced evidence of symptom relief. Turmeric also supports immune function is anti-bacterial, and is helpful in preventing blood clots. There is also some preliminary evidence that curcumin may help break up the proteins that appear to be the root cause of Alzheimer's disease. Turmeric has Generally Recognized as Safe (GRAS) status in the US.

Ginger (Zingiber officinale) is used as an anti-inflammatory agent and has been tested and found to be effective in the treatment of osteoarthritis and rheumatoid arthritis. Ginger has been found in laboratory studies to inhibit a number of factors associated with joint pain and damage.

Bromelain are enzyme which breaks down proteins and have been shown to be helpful in reducing the pain in arthritis patients.

 

Rutin is a bioflavonoid which, in the same clinical study, was shown to increase the effectiveness of the oral enzymes, potentially because of its anti-oxidant activity.

 

BioPerine® (Black Pepper) is an essential element for increased absorption. Piperine, the main alkaloid from black pepper has been shown to substantially increase the bioavailability of the nutrients in foods and supplements. Piperine can turn a marginally effective therapeutic substance into a highly effective one by increasing its bioavailability and intracellular residency time.